The manuscript is derived from two words - "manu/manus" and "script" which means "hand" and "written" respectively. So, all the written material which has relevance to Ayurveda can be taken under Ayurveda manuscripts.

A manuscript is a handwritten composition on paper, bark, cloth, metal, palm leaf or any other material dating back at least 100 years that has significant scientific, historical or aesthetic value. Lithographs and printed volumes are not manuscripts. Manuscripts are found in hundreds of different languages and scripts. Often, one language is written in a number of different scripts. For example, Sanskrit is written in Oriya script, Grantha script, Devanagari script and many other scripts.

Manuscripts are distinct from historical records such as epigraphs on rocks, firmans, revefnue records which provide direct information on events or processes in history. Manuscripts have knowledge content.